From: http://www.anaesthesiamcq.com/AcidBaseBook/ab8_5.php
The table below provides a useful summary of some of the key points in differentiating the types of renal tubular acidosis.
Comparison of Major Types of RTA | |||
|
Type 1 |
Type 2 |
Type 4 |
Hyperchloraemic acidosis |
Yes |
Yes |
Yes |
Minimum Urine pH |
>5.5 |
<5.5 (but usually >5.5 before the acidosis becomes established) |
<5.5 |
Plasma potassium |
Low-normal |
Low-normal |
High |
Renal stones |
Yes |
No |
No |
Defect |
Reduced H+excretion in distal tubule |
Impaired HCO3reabsorption in proximal tubule |
Impaired cation exchange in distal tubule |